Per Duke Pediatric Cancer, “Although pediatric cancers are less common than adult malignancies, the impact of cancer on children and their families is nothing short of devastating. Over the past 40 years, cooperative research efforts (primarily through the Children’s Oncology Group) have resulted in dramatic increases in cure rates for most pediatric cancers. Nevertheless, substantial numbers of children with cancer still succumb to their disease, and even larger numbers of pediatric patients suffer significant long-term late effects because of the intensity of the therapies required to achieve cure. Research into the pathophysiologic mechanisms underlying pediatric tumors is essential to develop novel therapeutic approaches that will yield higher rates of cure and fewer side effects.
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